Japanese Doctor Who Lived to 105—his Spartan Diet, Views on Retirement, and Other Rare Longevity TipsPosted: September 3, 2020
Dr. Shigeaki Hinohara had an extraordinary life for many reasons. For starters, the Japanese physician and longevity expert lived until the age of 105.
When he died, in 2017, Hinohara was chairman emeritus of St. Luke’s International University and honorary president of St. Luke’s International Hospital, both in Tokyo.
Perhaps best known for his book, “Living Long, Living Good,” Hinohara offered advice that helped make Japan the world leader in longevity. Some were fairly intuitive points, while others were less obvious:
1. Don’t retire. But if you must, do so a lot later than age 65.
But Hinohara viewed things differently. “There is no need to ever retire, but if one must, it should be a lot later than 65,” he said in a 2009 interview with The Japan Times. “The current retirement age was set at 65 half a century ago, when the average life expectancy in Japan was 68 years and only 125 Japanese were over 100 years old.”
Today, he explained, people are living a lot longer. The life expectancy for U.S. in 2020, for example, is 78.93 years, a 0.08% increase from 2019. Therefore, we should be retiring much later in life, too.
Hinohara certainly practiced what he preached: Until a few months before his death, he continued to treat patients, kept an appointment book with space for five more years, and worked up to 18 hours a day.
2. Take the stairs (and keep your weight in check).
Hinohara emphasized the importance of regular exercise. “I take two stairs at a time, to get my muscles moving,” he said.
Additionally, Hinohara carried his own packages and luggage, and gave 150 lectures a year, usually speaking for 60 to 90 minutes — all done standing, he said, “to stay strong.”
He also pointed out that people who live an extremely long life have a commonality: They aren’t overweight. Indeed, obesity is widely considered one of the most significant risk factors for increased morbidity and mortality.
Hinohara’s diet was spartan: “For breakfast, I drink coffee, a glass of milk and some orange juice with a tablespoon of olive oil in it.” (Studies have found that olive oil offers numerous health benefits, such as keeping your arteries clean and lowering heart disease risk.)
“Lunch is milk and a few cookies, or nothing when I am too busy to eat,” he continued. “I never get hungry because I focus on my work. Dinner is veggies, a bit of fish and rice, and, twice a week, 100 grams of lean meat.”
3. Find a purpose that keeps you busy.
According to Hinohara, not having a full schedule is a surefire way to age faster and die sooner. However, it’s important to stay busy not just for the sake of staying busy, but to be active in activities that help serve a purpose. (The logic is that one can be busy, yet still feel empty and idle on the inside.)
Hinohara found his purpose early on, after his mother’s life was saved by the family’s doctor.
Janit Kawaguchi, a journalist who considered Hinohara a mentor, said, “He believed that life is all about contribution, so he had this incredible drive to help people, to wake up early in the morning and do something wonderful for other people. This is what was driving him and what kept him living.”
“It’s wonderful to live long,” Hinohara said in the interview. “Until one is 60 years old, it is easy to work for one’s family and to achieve one’s goals. But in our later years, we should strive to contribute to society. Since the age of 65, I have worked as a volunteer. I still put in 18 hours seven days a week and love every minute of it.”
4. Rules are stressful; try to relax them.
While he clearly promoted exercise and nutrition as pathways to a longer and healthier life, Hinohara simultaneously maintained that we need not be obsessed with restricting our behaviors.
“We all remember how, as children, when we were having fun, we would forget to eat or sleep,” he often said. “I believe we can keep that attitude as adults — it is best not to tire the body with too many rules.”
Richard Overton, one of America’s oldest-surviving World War II veterans, would have most likely agreed. Right up until his death at age 112, the supercentenarian smoked cigars, drank whisky and ate fried food and ice cream on a daily basis.
Hinohara might not have approved of Overton’s diet, but, to be fair, Overton did credit his longevity to maintaining a “stress-free life and keeping busy.”
5. Remember that doctors can’t cure everything.
Hinohara cautioned against always taking the doctor’s advice. When a test or surgery is recommended, he advised, “ask whether the doctor would suggest that his or her spouse or children go through such a procedure.”
Hinohara insisted that science alone can’t help people. It “lumps us all together, but illness is individual. Each person is unique, and diseases are connected to their hearts,” he said. “To know the illness and help people, we need liberal and visual arts, not just medical ones.”
In fact, Hinohara made sure that St. Luke’s catered to the basic need of patients: “To have fun.” The hospital provided music, animal therapy and art classes.
“Pain is mysterious, and having fun is the best way to forget it,” he said. “If a child has a toothache, and you start playing a game together, he or she immediately forgets the pain.”
6. Find inspiration, joy and peace in art.
According to The New York Times, toward the end of his life, Hinohara was unable to eat, but refused a feeding tube. He was discharged and died months later at home.
Instead of trying to fight death, Hinohara found peace in where he was through art. In fact, he credited his contentment and outlook toward life to a poem by Robert Browning, called “Abt Vogler” — especially these lines:
There shall never be one lost good! What was, shall live as before;
The evil is null, is nought, is silence implying sound;
What was good shall be good, with, for evil, so much good more;
On the earth the broken arcs; in the heaven a perfect round.
“My father used to read it to me,” Hinohara recalled. “It encourages us to make big art, not small scribbles. It says to try to draw a circle so huge that there is no way we can finish it while we are alive. All we see is an arch; the rest is beyond our vision, but it is there in the distance.”
Tom Popomaronis is a leadership researcher and vice president of innovation at Massive Alliance. His work has been featured in Forbes, Fast Company, Inc., and The Washington Post. In 2014, Tom was named one of the “40 Under 40” by the Baltimore Business Journal. Follow him on LinkedIn.
A history of increased exercise doesn’t affect the immediate physiological response (like a release of cortisol) during a stressful event, Weinshenker and Tillage explain. Instead, exercise increases behavioral resilience after stress exposure.
“This could suggest that increased exercise doesn’t impact our immediate feelings of stress, but does allow us to cope with stress in a healthier way,” the co-authors say.
In times of serious stress, people might turn to exercise to blow off steam and shake off nervous energy. However, despite anecdotal evidence, the link between working out and relieving stress isn’t well understood by scientists. Researchers haven’t yet pinned down exactly how exercise modulates stress in the brain and body, despite knowing that exercise benefits mental health.
In a recent study conducted in mice, researchers became one step closer to that understanding, discovering that exercise actually strengthens the brain’s resilience to stress. Exercise helps animals cope with stress by enabling an uptick in a crucial neural protein called galanin, the study suggests. This process influences stress levels, food consumption, cognition, and mood.
Leveraging this finding, researchers were able to genetically tweak even sedentary mice’s levels of galanin, shifts that lowered their anxious response to stress.
The study’s authors explain that this study helps pin down the biological mechanisms driving exercise’s positive effects on stress. While further human experiments are needed to confirm these findings, the researchers have practical advice for people looking to get these benefits: perform regular, aerobic exercise.
“Not exercising at all and then suddenly going for a hard 10 mile run just before a stressful event isn’t as helpful as regularly jogging 3 miles several days a week over several months,” researchers David Weinshenker and Rachel Tillage, tell Inverse by email.
That’s because, based on these results, a history of increased exercise doesn’t affect the immediate physiological response (like a release of cortisol) during a stressful event, Weinshenker and Tillage explain. Instead, exercise increases behavioral resilience after stress exposure.
“This could suggest that increased exercise doesn’t impact our immediate feelings of stress, but does allow us to cope with stress in a healthier way,” the co-authors say.
These findings were released Monday in the Journal of Neuroscience.
The search for the brain mechanisms — Research shows exercise protects against the deleterious effects of stress in both mice and humans. Galanin, that pivotal brain protein that modulates stress and mood, is expressed in similar areas of both animal’s brains.
To examine how these factors interact and influence each other, the study team turned to mice.
“Mechanistic questions are difficult to answer in humans due to ethical and technical limitations, so we used mice for this purpose,” Weinshenker and Tillage say. With these overlapping properties, the team adds that the neurobiological substrates underlying galanin’s role in physical activity-related stress resilience could occur across species.
“One of the major implications from this study in that the galanin system could be a potential target for future therapies… “
The measured mice’s anxious behavior 24 hours after a foot shock test — aka the stressful event. They also analyzed their levels of galanin and examined its source.
Half the mice had regular access to an exercise wheel in their cage, while others had no running wheel. Mice steadily increased their running distance over the first week, after which they ran approximately 10-16 kilometers per day. Researchers tracked the mice’s activity for three weeks.
Aerobic exercise, like biking, is more likely to have a greater effect on stress resilience than non-aerobic exercise.
Those who exercised showed less anxious behavior after the stressful event compared to mice that didn’t exercise. Exercising mice also had elevated galanin levels in the locus coeruleus, a cluster of neurons in the brainstem involved in the stress response.
The amount of time the mice spent exercising in the third week correlated with the amount of galanin in the locus coeruleus, which in turn correlated with their degree of stress resilience.
Based on these findings, the team then genetically increased galanin in the locus coeruleus in sedentary mice. This gave these inactive mice exercise’s beneficial stress resilience effects, without changing their physical activity patterns.
If further human experiments confirm these findings, it could mean hijacking the galanin system could help people gain exercise’s stress resilience benefits, even if they aren’t able to work out.
“These findings build on what we know by isolating a specific biological mechanism — increased galanin in the locus coeruleus— by which exercise can influence how we respond to stress,” Weinshenker and Tillage explain. “One of the major implications from this study in that the galanin system could be a potential target for future therapies to gain the positive effects of exercise on stress resilience for people who are not able to exercise.”
Interestingly, the increased galanin didn’t influence other aspects of the mice’s behavior, suggesting galanin may be recruited only during periods of high stress, the team says.
More human data is needed to figure out exactly what type or how much exercise confers this stress-resilience effect. But based on the current evidence, the researchers say they can offer some general guidance:
- Aerobic exercise (like walking, running, biking, swimming) probably has a greater effect on stress resilience than non-aerobic exercise (like weight lifting).
- Exercise probably needs to be routine; completed a few times a week. Cramming in a HIIT workout or long run right before a stressful event isn’t likely to be as helpful as regularly hiking or hitting the elliptical.
Processed Foods age the body and lead to inflammation.
As humans get older, telomeres — the protective caps on the ends of our chromosomes — naturally shorten due to oxidative stress and inflammation. As they shrink, people become more likely to get sick with certain diseases and ultimately, die younger.
Ultra-processed foods are industrial creations often devoid of nutrients and whole foods. Instead, they are complete with a long list of additives, including oils, fats, sugars, starch, protein isolates, flavorings, colorings, emulsifiers, and other cosmetic additives.
They’re also often cheap to make, convenient for consumers, and can last years on the shelf. Think sugary cereals, canned soup, and white bread — tasty foods that line our pantries, but hurt our health.
According to this study, which analyzed the diets and telomere lengths of 886 people, ultra-processed foods appear to make cells age faster. People who ate more than three servings of ultra-processed foods daily were twice as likely to have short telomeres than people who opted out of these nutrient-poor foods.
“It is not well known the effect of the cocktail of all additives included in ultra-processed food on the long-term health of the population,” study co-author Maira Bes-Rastrollo, a researcher at the University of Navarro, tells Inverse.
Still, based on these findings, people should lower the amount of ultra-processed foods below three servings per day, Bes-Rastrollo advises. To slow cellular aging, she advises adopting a Mediterranean diet, one that’s complete with a high intake of fruits, vegetables, fish, and olive oil.
Currently, ultra-processed foods make up an estimated 60 percent of the average American’s diet. While it may be challenging to limit intake, your longevity could depend on it, these findings suggest.
This research was presented at this year’s European and International Conference on Obesity (ECOICO 2020), held online between September 1-4. They were previously published in the American Journal of Clinical Nutrition.
Past research links ultra-processed foods with negative health outcomes like hypertension, obesity, metabolic syndrome, depression, type 2 diabetes, and various cancers. But researchers hadn’t yet explored this type of food’s impact on telomere length, a vital metric of cellular aging.
To fill in this research gap, scientists harnessed data from the SUN Project. In 1999, the SUN Project recruited participants who had graduated from the University of Navarra and other Spanish universities. Then, scientists collected data from this cohort through self-reported questionnaires mailed out every two years.
A decade after the project kicked off, 886 participants over the age of 55 provided saliva samples for DNA analysis along with their daily food intake. The scientists extracted DNA from the saliva to measure telomere lengths.
In total 645 men and 241 women were split into four groups based on their UPF consumption. The groups included: less than 2 servings a day, 2 to 2.5 servings a day, more than 2.5 to 3 servings a day, and more than 3 servings a day.
In the group, the main contributors to ultra-processed food consumption were:
- 17 percent: dairy products (custard, ice cream, milkshake, and petit suisse)
- 15 percent: processed meat (ham, chorizo, mortadella, salami, pate, black pudding mortadella, sausages, hamburgers, and sobrasada)
- 12 percent: pastries (muffins, doughnuts, croissants, or other non-handmade pastries and confectionary)
- 9 percent: cookies
- 9 percent: sugar-sweetened beverages
The researchers found that, as ultra-processed food consumption went up, the likelihood of having shortened telomeres dramatically rose.
The quartile above the lowest category jumped 29 percent in the medium-low group, 40 percent in the medium-high group, and 82 percent in the high UPF consumption group. Participants with the highest ultra-processed food consumption had almost twice the odds of having short telomeres compared with those with the lowest consumption.
Bes-Rastrollo and her colleagues predict this troubling effect stems from higher total intakes of salt, saturated fat, and sugar, as well as inadequate intakes of fiber and micronutrients. They hope to replicate these findings with long term studies on larger populations.
Eating for cell health— A plate of cookies or sausage sandwich does not seem to acutely shorten telomeres. Instead, habitually consuming these foods seems to cause other health problems that eventually shorten them.
“Probably, the shorter telomere is a consequence of other health costs that finally produce oxidative stress and inflammation,” Bes-Rastrollo says.
Jibing with this prediction, ultra-processed food intake was also associated with increased risk of depression (especially in patients with low levels of physical activity), hypertension, being overweight or obese, and dying for any cause.
In the study, people with shorter telomeres ate higher services of ultra-processed foods and fewer servings of fruits and vegetables.
Participants who ate a diet heavy in ultra-processed foods were also more likely:
- Have a history of heart disease, diabetes, and abnormal blood fats.
- To snack more between meals, consumers more fats, salt, fast foods, and processed meat.
They were less likely to consume carbohydrates, olive oil, fiber, protein, fruits, vegetables, and other micronutrients.
Across the board, participants who ate more ultra-processed foods were less likely to adhere to the Mediterranean diet — the very diet Bes-Rastrollo recommends.
“Whole foods like fruits and vegetables, a key aspect of the Mediterranean diet, should be promoted and more education among the population on how to cook healthy and easy meals should be desirable,” Bes-Rastrollo says.
LONGEVITY HACKS is a regular series from Inverse on the science-backed strategies to live better, healthier, and longer without medicine.
HOW THIS AFFECTS LONGEVITY — Researchers discover that ultra-processed foods seem to accelerate cellular aging by shortening telomeres, the protective caps on the ends of chromosomes.
WHY IT’S A HACK — It can be hard to break eating habits, but cutting down to three servings a day of these nutrient-poor foods could help you live longer and healthier.
SCIENCE IN ACTION — On a daily basis, swap out french fries for Brussel sprouts or skip the soda and opt for green tea. You can even make your beef enchilada veggie — small tweaks can add up to meaningful health outcomes over a lifetime.
HACK SCORE OUT OF 10— (To protect telomeres, keep tasty, low nutrient foods below three servings a day, nutrition experts say)
Background: Telomere length (TL) is a marker of biological age that may be affected by dietary factors through oxidation and inflammation mechanisms. In addition, ultra-processed food (UPF) consumption has increased worldwide and it has been associated with the risk of developing several diseases.
Objectives: We aimed to evaluate the association between UPF consumption and the risk of having short telomeres in an elderly population of the Seguimiento Universidad de Navarra (SUN) Project.
Methods: This is a cross-sectional study of 886 participants (645 men and 241 women) aged 57–91 y recruited from the SUN Project (Spain, 1999–2018). TL was measured from saliva samples by real-time qPCR at baseline and UPF consumption was collected using a validated 136-item FFQ and classified according to the NOVA system. We evaluated the association between consumption of energy-adjusted UPF categorized into quartiles (low, medium-low, medium-high, and high consumption) and the risk of having short telomeres (<20th percentile) using logistic regression models.
Results: Those participants with the highest UPF consumption had almost twice the odds of having short telomeres compared with those with the lowest consumption (adjusted OR: 1.82; 95% CI: 1.05, 3.22; P-trend = 0.03).
Conclusions: A higher consumption of UPF (>3 servings/d) was associated with higher risk of having shorter telomeres in an elderly Spanish population of the SUN Project.
Millie- Even though I have always used organic or natural skin and makeup choices I have been alarmed at how many so-called natural and organic products contain silicones. Another chemical that most organic products have is Butylene glycol. It is a petroleum product that hey consider organic. The word organic means nothing more than “ noting or pertaining to a class of chemical compounds that formerly comprised only those existing in or derived from plants or animals, but that now includes all other compounds of carbon”. It has been tough finding effective skin products without these items. While I can tolerate silicones with no reaction, I do find that using products with them makes my serums and moisturizers less effective. The reason for this is that silicones sit on top of the skin and form a barrier, so that treatments aren’t effective as they do not reach the skin. So my oils and moisturizers cannot nourish the skin. Also it does not let the skin breath properly. I have spent a year experimenting with my skin care, and my skin looks far better with products that are not occlusive to his degree.
Have you ever wondered what makes your favourite moisturizer light as air and non-greasy? It’s simple: you can thank silicone for that kind of texture.
Yes, silicone – the umbrella term for a countless number of synthetic polymers whose place in clean beauty has been called into question on more than one occasion. However, silicones aren’t new to the industry.
First introduced in the ’50s, cosmetic grade synthesized silicon-carbon polymers (also known as silicones) offered companies a number of characteristics that made improving the feel, appearance, and performance of cosmetic products infinitely better.
Today, silicone compounds are being developed in many different shapes and forms, from fluids to powders. In natural products, like sunscreen, an emollient called dimethicone gives life to some of the most luxurious, desirable textures on the market.
The downside? Like any other synthetic ingredient, there have been negative effects associated with prolonged use of dimethicone on the skin. The verdict on this ingredient amongst industry professionals is truly a mixed bag, which makes forming an opinion about whether or not its a “good” or “bad” substance a bigger challenge.Though some might suggest avoiding silicones like dimethicone at all costs, it may not be necessary.
Here, you’ll discover all you need to know about dimethicone and its benefits. Plus, Sara A. Dudley, CEO of The Sunscreen Company, weighs in on dimethicone in sun care products.
What is dimethicone?
By definition, silicone is a synthetic polymer made up of silicon, oxygen, and other elements like carbon and hydrogen. Dimethicone works well with humectants – agents that help retain the skin’s moisture levels.
Found prominently in creams, lotions and primers for its ability to moisturize the skin without feeling heavy, dimethicone is frequently used as a substitute for petrolatum-based ingredients.
The silky, spreadable texture of dimethicone allows products to be applied smoothly and fills in wrinkles and fine lines, resulting in an even appearance. These properties often produce an effect that makes you think a product is “working” despite the fact that its effects are temporary.
Why use it?
Back in 2017, founder and editor of The Skincare Edit, Michelle Villett, summed up the reasons why silicones like dimethicone are used by brands in the most concise way: they’re smoothing, water resistant, and they’re inexpensive for companies to purchase and include in their formulas.
Aside from moisturizing and smoothing skin without feeling heavy, dimethicone can also be used to treat sensitive skin.
“It can actually help people with compromised skin barriers because it’s occlusive. For my infant son, for example, we use a body moisturizer that has a little dimethicone in it for his eczema because he needs the added protection,” said Dudley.
Although Dudley views the dimethicone “grey zone” in clean beauty as an interesting topic, she doesn’t believe the product is actually harmful to the skin.
“It has been overused in a lot of conventional products because it tricks consumers into thinking it’s giving extra hydration. It will make skin or hair look good in the short term but it’s not really treating or hydrating the skin in a beneficial way,” she explained. “From a sunscreen standpoint, it can help with spreadability, especially for mineral sunscreens that have really large particulates in them.”
A long-standing debate persists about whether or not silicones like dimethicone cause clogged pores, irritation and prevent other ingredients from absorbing into the skin. However, it’s been said that there’s no scientific basis for those claims, since silicones are “pure synthetics” specially formulated to avoid clogging pores and irritating the skin.
Another reason why dimethicone is viewed negatively is because of its occlusive nature, which forms a barrier on the skin that’s been said to “exacerbate acne” by trapping moisture, bacteria, sebum, and other impurities.
Dudley notes consumers concern about the bioaccumulation of particles from silicones in water systems, and for this reason, The Sunscreen Company has removed it from their products.
“I think it gets a bad rap as being not natural, although I would argue it’s just further down the chain of what is considered naturally derived,” said Dudley. “It’s considered a cheap ingredient or filler, something designed by big brands to dupe customers. I think it can have a place in clean beauty, but it just needs to be used a lot more judiciously and transparently than what has been done in the past.”
After weighing both sides of the case on dimethicone, it turns out that your judgement is the most important factor in deeming how safe or unsafe it is to use on the skin.
To learn more about the potentially adverse affects on the body and the environment related to dimethicone, EWG’s Skin Deep is a great resource. The scientific findings about dimethicone’s “harmfulness” are limited, though its been proven time and time again to serve as a less toxic alternative to pesticide-containing products.
#mealdeliveryservice, #jax,#lactosefree,#glutenfree,#JacksonvilleFL,#nutritioncoaching, #allergies,#cancer,#energy,#higherenergy,#healing, #beyondpaleo, #immunesystem, #weightloss, #energy #pontevedrabeach, #atlanticbeach
Coconut- Macadamia Crust with Lime Curd, Sliced Mangoes and a Guava Glaze
Serving Size : 10
2 1/2 cups roasted macadamia nuts (about 10 ounces)
1 7/8 cups sweetened shredded coconut
1 5/8 cups almonds- sliced
5/8 cup golden brown sugar — (packed)
3 3/4 large egg whites
1 1/4 cups sugar
½ cup fresh lime juice
12 1/2 large egg yolks
5/8 cup chilled unsalted butter — (1 stick) cut into pieces
Make crust: Preheat oven to 350°F. Butter eight 4-inch-diameter tartlet pans with removable bottoms with butter, preferably ghee. Combine nuts, coconut and brown sugar in processor. Process until nuts are finely chopped. Transfer to large bowl. Beat egg whites in another large bowl until soft peaks form. Fold whites into nut mixture in 3 additions (mixture will be thick and sticky). Let mixture stand 10 minutes.
Using plastic wrap as aid, press about 1/3 cup nut mixture onto bottoms and up sides of each prepared pan. You can use individual tart pans, a large tart pan or a non-stick large muffin pan to make individual tart crusts. Place pans on baking sheet. Bake until crusts are puffed and begin to brown, about 20 minutes. Cool crusts in pans 5 minutes. Using oven mitt, gently remove pan sides; cool crusts completely on rack.
Make lime curd: Whisk sugar, lime juice and yolks in large metal bowl to blend. Set bowl over saucepan of simmering water; whisk constantly until mixture thickens and candy thermometer registers 180°F., about 9 minutes. Gradually add chilled butter, whisking until melted and well blended. Press plastic wrap directly on surface of curd. Refrigerate until cold, about 3 hours.
Fill each crust with 5 tablespoons lime curd. Arrange mango slices decoratively atop tartlets. Whisk guava jelly in heavy small saucepan over low heat until melted. Brush over mango slices.
3 tablespoons distilled white vinegar
3 tablespoons sugar or honey
6 tablespoons Dijon mustard
6 tablespoons mayonnaise
4 large pickling cucumbers, peeled, cut into 1/2-inch cubes (about 2 cups)
2 large mango, peeled, pitted, cut into 1/2-inch cubes (about 1 1/2 cups)
1 pound cooked medium shrimp
3 tablespoons chopped fresh dill
Hot pepper sauce
Mix vinegar and sugar in small bowl until sugar dissolves. Whisk in mustard and mayonnaise. Cover and chill.
Combine cucumbers, mango, shrimp, and dill in large bowl. Pour dressing over; toss to coat. Season with salt and hot pepper sauce.
June 7, 2020 — 11:20 AM
The concept of microdosing is all the rage these days—and for a good reason. Microdosing refers to the practice of taking tiny portions of a substance, usually around one-tenth or one-twentieth of a normal dose. The idea is to reap the positive benefits of a substance, without any of the negative.
What’s more, everyone’s body is different, so people respond to substances in their own unique way. Plus, sometimes it’s easier to ramp up something slowly rather than go straight for the higher dose, which is why I often recommend microdosing to my patients in various contexts. Recently, one practice I’ve been fascinated with is microdosing caffeine.
What is caffeine microdosing?
To achieve an optimal energy zone, you generally need to consume between 60 mg and 100 mg of caffeine. Plus, your overall ability to concentrate and perform is more ideal when you can remain in this sweet spot over a steady period of time. To put that into perspective, one cup of coffee generally contains about 100 mg of caffeine, a shot of espresso is 85 mg of caffeine, and a cup of green tea is 40 mg of caffeine.
One way to optimize your intake is through microdosing, or consuming small amounts of caffeine throughout the day. This might look like drinking a cup of coffee in the morning, and then only having green tea throughout the rest of the day. Or slowly sipping your coffee in the morning, which may help you drink around 10 mg or so of caffeine at a time. These techniques may give you enough stimulation to help you be as productive as possible without feeling jittery or anxious.
The benefits of caffeine, even in small doses.
While too much caffeine can cause negative side effects like anxiousness or a rapid heartbeat, there is a lot of evidence in scientific literature regarding caffeine, its health benefits, and its potential as a microdosing agent.
In addition to increasing energy and improving cognition, there is also some research that indicates it may affect inflammatory conditions and autoimmunity. Other literature suggests that natural caffeine sources like coffee may help prevent prediabetes and type 2 diabetes.
Caffeine has also been researched since the 1970s as a performance-enhancing substance, for athletes and military, but often at moderate to high doses. However, what we are finding now is that low doses can be safer and better for the body: They can help improves alertness, mood, and cognition during and after physical exercise but with few (if any) side effects. In fact, a recent review suggested that low doses of caffeine, as low as 3 mg, can be just as effective as higher doses.
What’s more, scientists at Harvard did a randomized, double-blind placebo-controlled study where 16 male subjects microdosed caffeine for, and were sequestered for, 29 days. They were also deprived of time cues so they could simulate the extended wakefulness that doctors, military, and emergency services first responders often experience. What the researchers found was that those who took the low-dose caffeine supplement performed better on cognitive tests and had fewer accidental sleep onsets. The results suggest that microdosing caffeine can be especially helpful in circumstances in which an individual must wait for the opportunity for a good night of restorative sleep (think essential workers).
Should you try microdosing caffeine?
When patients are interested in optimizing their nutrient and vitamin levels, I often run a nutritional genomics panel. When I do this, one of the common genes that is tested for is a gene that affects caffeine metabolism. If a patient has a gene mutation in the CYP1A2 gene, they have an increased risk of high blood pressure or heart attack if they drink more than 200 mg of caffeine daily.
This is all to say that some people are more sensitive to caffeine than others. Maybe you’ve already noticed this about yourself anecdotally—perhaps after having two cups of coffee you feel shaky or anxious. For context, most people tend to get into the jitter zone when they hit 140 mg to 200 mg, which is often the case when drinking energy and power drinks.
Regardless of how you metabolize caffeine, taking it in small amounts can help you hone in on the exact dose you need to optimize your focus, creativity, mood, and energy without worrying about what happens when you “crash” from the caffeine high and start getting headaches and other side effects.
Cautions for caffeine microdosing.
One thing I always like to caution people about is reading labels. You want to make sure that your good intentions are not negated by taking a product that has other unhealthy ingredients mixed in or contains caffeine from an unnatural source.
I always advise my patients to look for labels such as “from a plant source” like green coffee beans or green tea leaves, for example. If this isn’t disclosed on the label, it’s possible that the product you are taking could be synthetic and made in a lab. Also there are more health benefits from using a natural source of caffeine rather than a synthetic processed form. Like with anything you ingest, make sure the products are true to their purpose.
Also, please remember that it is important to consult with your doctor before trying something new, like caffeine microdosing.
Microdosing can be a useful way to reap the benefits of caffeine. Especially if you are a slow caffeine metabolizer like me, it can help you avoid unwanted side effects from excess coffee. Just be sure to speak to your doctor before making any drastic changes to your nutrition routine.
Ready to learn how to fight inflammation and address autoimmune disease through the power of food? Join our 5-Day Inflammation Video Summit with mindbodygreen’s top doctors.
Marvin Singh, M.D is an Integrative Gastroenterologist in San Diego, California, and a Member of the Board and Diplomate of the American Board of Integrative Medicine. He is also…
Hypertension: Celery contains potassium, which counters the harmful effects of sodium
“Celery stalk salt content is low, and you also get fibre, magnesium and potassium to help regulate your blood pressure, as well,” notes Cleveland Clinic.
Foods that are rich in potassium are particularly important in managing high blood pressure because potassium lessens the effects of sodium, according to the American Heart Association (AHA).
Sodium, which is found in salt, raises your blood pressure, but the more potassium you eat, the more sodium you lose through urine.
“Potassium also helps to ease tension in your blood vessel walls, which helps further lower blood pressure,” explains the AHA.
HIGH blood pressure doesn’t produce symptoms so the only way to keep it in check is to make healthy lifestyle decisions. Eating a healthy diet is a surefire way to reverse high blood pressure and no diet would be complete without this green snack.
High blood pressure is when your blood pressure, the force of blood flowing through your blood vessels, is consistently too high. Over time, this causes your blood vessels to lose their elasticity, restricting the amount of blood that flows through them. Restricting the supply of blood to your heart is particularly concerning because it can trigger a heart attack.
Unfortunately, high blood pressure does not usually have any symptoms, so the only way to find out if you have it is to get your blood pressure checked.
According to the NHS, blood pressure tests can also be carried out at home using your own blood pressure monitor.
Blood pressure is measured in millimetres of mercury (mmHg) and is given as two figures.
Systolic pressure – the pressure when your heart pushes blood out – is the top number and diastolic pressure – the pressure when your heart rests between beats – is the bottom number.
“High blood pressure is considered to be 140/90mmHg or higher (or an average of 135/85mmHg at home) – or 150/90mmHg or higher (or an average of 145/85mmHg at home) if you’re over the age of 80,” explains the health body.
If the test determines that your blood pressure is too high, you must make healthy lifestyle decisions to lower it.
Overhauling your diet plays a key role and a robust body of evidence can point you to the most heart-healthy items.
According to research, snacking on celery can help to combat high blood pressure.
your physician before using this exercise equipment or beginning any exercise program.” It’s a well-intended message designed to be responsible and keep people safe.
But scientists called for public warnings with exactly the opposite message at a satellite symposium that was organized by the American Society for Nutrition on Friday, April 25. The event, sponsored by Herbalife Nutrition Institute, took place at Experimental Biology in San Diego.
Endocrinologist Dr. David Heber, director of the UCLA Center for Human Nutrition, reminded that a sedentary lifestyle has disastrous pathologic consequences. He said that, combined with obesity, physical inactivity leads to abdominal adiposity, visceral fat, chronic systemic inflammation, insulin resistance, and ultimately diabetes and cardiovascular disease.
Underlining the consequence of protein breakdown due to physical inactivity, Dr. Heber counseled that the muscle loss and a subsequent drop in resting metabolic rate puts the U.S. population at risk of widespread sarcopenic obesity. Muscle burns 30 Kcals per kilogram versus fat’s only 6 Kcals per kilogram, he reminds.
Former U.S. surgeon general Dr. Richard Carmona said that the problems of getting people to do more for their health wasn’t a matter of needing more knowledge or authority. “It’s getting people to listen,” he said. “Where we have failed is really in the translation. We need better translators of science.”
Sharing some of his 2002-2006 term experiences, Dr. Carmona illustrated how obesity was burdensome to the country by ways of high costs — and even to national security. After Hurricane Katrina, for example, he said a lot of the people affected had low health literacy, were obese, and had several medical conditions related to obesity such as high blood pressure and type 2 diabetes. These issues exacerbated the tragic event.
“Obesity doesn’t get the attention it deserves,” he said. “Health care is really sick care and it’s driven by obesity.”
University of Colorado Professor of Pediatrics and Medicine James Hill, Ph.D., said regular physical activity of an hour or more daily was one of the behaviors that has shown to be key in leading to long-term weight management success, according to the National Weight Control Registry of which he co-founded. The registry follows more than 6,000 formerly obese people who have lost weight and kept it off permanently.
But the reason physical activity is important had little to do with burned calories, he explained. “In my opinion,” he said, “the important point is that it helps our bodies operate in the way they’re meant to operate.”
Hill said once physical activity reaches a specific threshold it has a way of adjusting the body’s appetite according to energy expenditure. Showing a figure modified from the work of Jean Mayer and colleagues, he illustrated the concept of the physical activity threshold explaining that to the left of the bar was an unregulated zone and to the right there was a regulated zone.
“Our biology works best at high level of physical activity. Energy expenditure is driving the bus,” he said. “But most of us are left of the bar.”
Most now includes 88.9 percent of the world population in 122 countries, according to professor of epidemiology and kinesiology Bill Kohl, Ph.D., of University of Texas at Austin’s Department of Kinesiology and Health Education.
In July 2012, Kohl reported conclusions in The Lancet that one out of three (31.1 percent) adults didn’t meet physical activity guidelines of 150 minutes per week, that men were more active than women, that inactivity increases with age, that inactivity is higher in high-income countries. In addition, he found that four out of five (80.3 percent) adolescents didn’t meet guidelines of 60 minutes per day and that boys were more active than girls.
Throughout the world, Kohl said, overall physical activity is declining rapidly. He cited research of Timothy Church and colleagues, as well as a review paper by Shu Wen Ng and Barry Popkin, showing that one of the major reasons had to do with drastically declining from occupational physical activity.
“I submit to you that this isn’t just a weight loss problem,” he said. “It’s a pandemic. If the number of people in the world that were physically inactive were smoking, we’d be up in arms. We should be up in arms.”
How much physical activity should one do to gain an impact? There’s a dose-response effect, according to John Jakicic, Ph.D., professor and chair of the University of Pittsburgh department of health and physical activity.
Based on his prior research and from Goodpaster et al and Slentz et al (and unpublished data he shared), he said that the higher level of physical activity one has, the greater the body weight change, the greater impact on visceral adiposity, and greater reduction of HbA1c (glycated hemoglobin).
Rather than put up warnings about exercise, he said, why not put up a new cautionary statement: “Physical inactivity has been shown to be associated with increased mortality, morbidity, and lower quality of life. Please consult with your physician if you decide not to engage in regular periods of daily physical activity.”
Dr. Julian Alvarez Garcia of University of Alicante (Spain), reminded that exercise is a “very complex phenomenon.” Athletes, for example, will often time nutrition before, during, or after exercise to fuel specific adaptations such as for weight loss, endurance, or strength.
Moving what he called “a step beyond energetics,” Dr. Garcia suggests that a different mindset be used when eating. We shouldn’t think of nutrition as feeding exercise, but “feeding adaptation,” he said.
Avoid dairy and gluten containing foods, exercise and stop smoking..
First it’s important to understand how the virus attacks our lungs. When people are infected, the virus travels to the mucus membranes and then the lungs. To control the infection, the body responds with inflammation in the lungs. And this inflammation prevents the lungs from being able to oxygenate the blood and remove carbon dioxide, which leads the patient to gasp for air and suffer more serious illness.
But there are things you can do to improve respiratory health, just by changing a few lifestyle factors, according to Dr. Robert Eitches, an allergist and immunologist at Cedars-Sinai Medical Center in Los Angeles. Enhancing your respiratory health doesn’t prevent you from getting infected, he said. But it does have benefits that may reduce the severity of the illness if you are infected, and therefore your exposure to the virus.
Here’s how you can strengthen your body’s respiratory capacity so that if you do get infected with coronavirus, the chances of serious illness may be lower.
Reduce excess mucus buildup
“Mucus is naturally occurring in our bodies, and it provides a very important function to maintain good health in our respiratory tract,” Steele said. “It helps to capture [allergens, bacteria and viruses].”
In our respiratory tract, we have little hairs called cilia that move those threats out of our tract. We swallow the majority of mucus, Steele said, but when we have things that irritate our nasal passages, we can produce too much mucus and be unable to clear it. This creates a breeding ground for bacteria and viruses, and blocks oxygen from entering and leaving the pathways of the lungs.
We also have mucus in our lungs. People with asthma produce too much mucus, which can predispose them to blockages and inflammation in their airways, Steele said.
There may be a connection between diet and mucus buildup. “Some people believe that inflammatory foods such as milk and wheat increase mucus production,” Eitches said. “Another school of thought that I have seen to work both anecdotally with my patients and with myself is eating spicy foods.”
Spicy foods that have capsaicin — chiles, jalapenos, cayenne, hot sauce — can thin mucus and allow it to be coughed out.
Exercise can improve respiratory capacity, or breathing ability. Alveoli are tiny, balloon-shaped air sacs arranged in clusters throughout the lungs. They’re integral to the respiratory system, as they exchange oxygen and carbon dioxide to and from the bloodstream.
When a person is sedentary, Steele said, that results in a phenomenon called “atelectasis,” when the lung sacs don’t have enough air and collapse slightly. To improve the lung sac capacity, people have to “breathe against resistance,” he added.
“You can think of it like a partially deflated balloon,” he suggested. “And what’s the way that you keep the air inside a balloon? You tie a knot in it to increase the resistance, so the air has to work harder to get out.”
By breathing against resistance when exercising, you’re “actually helping to expand and keep open the air sacs” in your lungs, Steele said.
In addition to cardio, yoga and stretching, breathing exercises such as pursed lip breathing and deep yogic nasal breathing can help and are easy to do wherever you are, Eitches suggested. Pursed lip breathing is when you take in a deep breath with your mouth, close your lips, then exhale through them as if you’re blowing up a balloon. There are similar benefits from deep yogic nasal breathing as you filter the air through your nose.
Improving your lung function means “you would be less likely to hit a critically low lung function state, which would in turn cause you to not be able to oxygenate your blood,” Eitches said.
“Respirators essentially breathe for you to try to push open your airways. These exercises will teach you how to fight off the respiratory side effects [of Covid-19] on your own.”
Additionally, Steele said, exercise decreases inflammation in the body and can reduce the occurrence of acute respiratory distress syndrome, a serious complication in some patients hospitalized with Covid-19.
One of the most important steps to improving your respiratory health is avoiding anything that impairs lung function, such as smoking cigarettes and vaping, Eitches said.
Smoking and vaping cause irritation in the lung airways that leads to permanent, adverse effects on lung function by destroying lung tissue where air exchange occurs.
“Smoke is composed of small particles; when inhaled, the particles get stuck in the lungs,” Eitches said. “This begins a vicious cycle of permanent lung damage.”
Both activities can also suppress the immune system, which you need to be able to help fight infections.
Dr. Ryan Steele, an allergist-immunologist and assistant professor at the Yale School of Medicine, cautioned against smoking marijuana, too.
Many candles have metal wicks, which are vaporized along with smoke and can cause similar lung damage.
Taking steps to improve respiratory health is another tool to add to one’s prevention kit, as we weather the pandemic and anticipate another possible wave in the fall.
“The stronger your baseline health, the stronger your body will be to fight off infections,” Eitches said. “It’s like having the appropriate ammunition to fight a war.”
CNN’s Brian Fung and Jen Christensen contributed to this report.